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Forschung > Virologie > AG von Brunn > Publikationen > 

Publikationen aus gegenwärtigen Projekten:

Ma-Lauer, Y., Lei, J., Hilgenfeld, R. and von Brunn, A. Virus-host interactomes - antiviral drug discovery. (2012). Current Opinion in Virology 2, 614-621.

Carbajo-Lozoya, J., Müller, M.A., Kallies, S., Thiel, V., Drosten, C. and von Brunn, A. (2012). Replication of human coronaviruses SARS-CoV, HCoV-NL63 and HCoV-229E is inhibited by the drug FK506. Virus Research 165, 112–117.

Häuser, R., Blasche, S., Dokland, T., Haggård-Ljungquist, E., von Brunn, A., Salas, M., Casjens, S., Molineux, I. and Uetz, P. (2012). Baceriophage protein-protein interactions. Advances in Virus Research 83, 219-298.

Stellberger, S., Häuser, R., Uetz, P. and von Brunn, A. (2012). Yeast Two-Hybrid Screens: Improvement of array-based screening results by N- and C-terminally tagged fusion proteins. Methods Mol Biol. ;815:277-88.

Pfefferle, S., Schöpf, J., Kögl, M., Friedel, C., Müller, M.A., Carbajo-Lozoya, J., Stellberger, T., von Dall'Armi, E., Herzog, P., Kallies, S., Niemeyer, D., Ditt, V., Kuri, T., Züst, R., Pumpor, K., Hilgenfeld, R., Schwarz, F., Zimmer, R., Steffen, I., Weber, F., Thiel, V., Herrler, G., Thiel, H.-J., Schwegmann-Weßels, C., Pöhlmann, S., Haas, J., Drosten, C. and von Brunn, A. (2011). The SARS-Coronavirus-Host Interactome: Identification of Cyclophilins as Target for Pan-Coronavirus Inhibitors. PLoS Pathog 7(10): e1002331.

Lei, J., Mesters, J.R., von Brunn, A. and Hilgenfeld, R. (2011) Crystal structure of the middle domain of human poly(A)-binding protein-interacting protein 1. BBRC 408 (4): 680-685.

Fossum, E., Friedel, C.C., Rajagopala, S.V., Titz, B., Baiker, A., Schmidt, T., Kraus, T., Stellberger, T., Rutenberg, C., Suthram, S., Bandyopadhyay, S., Rose, D., von Brunn, A., Uhlmann, M., Zeretzke, C., Dong, Y.A., Boulet, H., Koegl, M., Bailer, S.M., Koszinowski, U., Ideker, T., Uetz, P., Zimmer, R., Haas, J. (2009). Evolutionarily conserved herpesviral protein interaction networks. Evolutionarily conserved herpesviral protein interaction networks. PLoS Pathog. 2009 Sep;5(9):e1000570.

von Brunn, A., Teepe, C., Simpson, J.C., Pepperkok, R., Friedel, C.C., Zimmer, R., Roberts, R., Baric, R., Haas, J. (2007). Analysis of Intraviral Protein-Protein Interactions of the SARS Coronavirus ORFeome. PLoS ONE 23;2:e459.

 

 

Konferenzen/Vorträge:

R. Hilgenfeld, J. Tan, Y. Kusov, C. L. Schmidt, Y. Ma-Lauer, A. von Brunn and J. Lei. “Acquisition of new protein domains by SARS-coronavirus: Functional and structural dissection of the SARS-unique domain (SUD) “. National Symposium on Zoonoses Research 2012, 11.-12.10.2012, Berlin (Vortrag).

A. von Brunn, Y. Ma-Lauer, S. Pfefferle, J. Carbajo-Lozoya, M. A. Müller, S. Kallies, V. Thiel, R. Hilgenfeld, S. Pöhlmann, F. Weber, G. Herrler, C. Schwegmann- Weßels, H.-J. Thiel and C. Drosten. „The SARS-Coronavirus-Host Interactome: Identification of  Cyclophilins as Targets for Pan-Corona-virus Inhibitors.“ National Symposium on Zoonoses Research 2012, 11.-12.10.2012,  Berlin (Vortrag).

Y. Ma-Lauer, J. Carbajo-Lozoya, M. A. Müller, S. Kallies, V. Thiel, C. Drosten and A. von Brunn. „Replication of human  coronaviruses SARS-CoV, HCoV-NL63 and HCoV-229E is inhibited by the drug FK506“. National Symposium on Zoonoses Research 2012, 11.-12.10.2012, Berlin (Vortrag).

A. von Brunn. “Applying systems biology to virus-host interactions”. 8.8.2012. (Einladungvortrag: Graduate Education Cluster of Excellence "Inflammation at Interfaces" University of Lübeck; Lecture at Summer School “Molecular Interactions at Barriers in  Inflammation”).

J. Carbajo, Marcel M. Müller, Stephan Kallies, Volker Thiel, Yue Ma-Lauer, Christian Drosten and Albrecht von Brunn. Replication of human coronaviruses SARS-CoV, HCoV-NL63 and HCoV-229E is inhibited by the drug FK506. Jahrestagung der Gesellschaft für  Virologie (GfV), 14.-17.-3.-2012 (Vortrag).

A. von Brunn. “Applying systems biology to Severe Acute Respiratory Coronavirus and its human host : Identification of  inhibitors against corona viruses by high-throughput screening of virus-host protein-protein interactions” 16.09.2011  Department of Cell and Molecular Biology, Centro Nacional de Biotecnologia, CSIC, Campus Universidad Autonoma, Cantoblanco, Madrid, Spanien (Einladungsvortrag).

A. von Brunn, S. Pfefferle, M. A. Müller, J. Schöpf, M. Kögl, F. Schwarz, C. Friedel, P. Herzog, S. Kallies, T. Stellberger, D. Niemeyer,
V. Ditt, T. Kuri, R. Züst, R. Zimmer, I. Steffen, F. Weber, V. Thiel, G. Herrler, H.-J. Thiel, C. Schwegmann-Weßels, S. Pöhlmann, C. Drosten. Identification of cyclophilins as targets for pan-Coronavirus inhibitors. XIIth International Nidovirus Symposium, June 4-9, 2011, Acme, Michigan, USA (Vortrag).

Susanne Pfefferle, Julia Schöpf, Manfred Kögl, Marcel A. Müller, Caroline Friedel, Petra Herzog, Stefan Kallies, Daniela Niemeyer, Vanessa Ditt, Thomas Kuri, Roland Züst, Ralf Zimmer, Imke Steffen, Friedemann Weber, Volker Thiel, Georg Herrler, Heinz-Jürgen Thiel, Christel Schwegmann-Weßels, Stefan Pöhlmann, Christian Drosten, A. von Brunn. “Identification of cyclophilins as targets for pan-Coronavirus inhibitors.” Jahrestagung der Gesellschaft für Virologie (GfV), 24.-29.-3.-2011 (Vortrag)

T. Stellberger, P. Herzog, D. Muth, C. Drosten, A. von Brunn. „Analysis of Intraviral Protein-Protein Interactions of the human Coronavirus NL63 ORFeome by Matrix-based Yeast-Two-Hybrid Screen”. Jahrestagung der Gesellschaft für Virologie (GfV), 24.-29.-3.-2011 (Poster)

A. von Brunn (LMU, Max von Pettenkofer-Institut). "Applying systems biology to Severe Acute Respiratory Coronavirus and its human host". LMU innovative – ANALYSIS AND MODELLING OF COMPLEX SYSTEMS IN BIOLOGY AND MEDICINE BioMed-S Retreat Höhenried, 22.-23. Juli 2010 (Einladungsvortrag).

A. von Brunn. “Applying systems biology to Severe Acute Respiratory Coronavirus and its human host : Identification of Cellular Targets and Inhibitors for intervention against SARS-CoV and other human and animal corona-viruses.” Tiermedizinische Hochschule Hannover, 17.11.2010 (Einladungsvortrag).

Schöpf, J., Pfefferle, S., Kögl, M., Herzog, P., Müller, M.A., Kallies, S., D. Muth, D., T. Kuri, T., Ebel, F., Friedel, C., Zimmer, R., Weber, F., Haas, J., Thiel, H.-J., Herrler, G., Schwegmannn-Wessels, C., Thiel, V., Drosten, C., von Brunn, A. Applying systems biology to Severe Acute Respiratory Coronavirus and its human host: identification of a cellular target and its inhibitor for antiviral intervention. 4th EUROPEAN CONGRESS of VIROLOGY
7 - 11 April 2010, Cernobbio, Lake Como, Italy (Vortrag).

Nationalen Forschungsplattform für Zoonosen“ (Innovative Approaches against Respiratory Viral Diseases): „Applying systems biology to Severe Acute Respiratory Coronavirus and its human host“ am 12./13.10.2009 in Berlin, A. von Brunn (Einladungsvortrag).

Nationales Symposium für Zoonosenforschung 2009: “On the way to cure: Identification of Cyclosporin A as inhibitor of SARS-CoV replication by analysis of virus-host protein- protein interactions via an undirected systems biology approach” am 7./8.10.2009 in Berlin, A. von Brunn (Einladungsvortrag).

Schöpf, J., Kögl, M., von Dall’armi, E., Endesfelder, M., Weber, F., Kuri, T., Glowaka, I., Bertram, S., Pöhlmann, S., Pfefferle, S., Drosten, C, Haas, J., von Brunn, A. Genome-wide analysis of protein-protein interactions between the SARS - coronavirus and the human host. Jahrestagung der Gesellschaft für Virologie (GfV), 18.-21. 03. 2009

Koegl, M., Baiker, A., Friedel, C., Dong, Y.-A., von Brunn, A., Fossum, E., Kasmapour, B., Schwarz, F., Zimmer, R., Haas, J., Korn, B. High-throughput screening for virus-host inter-actions. 2008 Cold Spring Harbor Laboratory/ Wellcome Trust conference on Network Biology; August 27 - 31, 2008; Hinxton, UK

Schöpf, J., Haas, J. and von Brunn, A. Genomweite Analyse von Protein-Protein Interaktionen zwischen dem SARS-Coronavirus und der humanene Wirtszelle. Sechstes BayGene Mitarbeiterkolloquium, 25.6.2008

Schöpf, J. and von Brunn, A. Genomweite Analyse von Protein-Protein Interaktionen zwischen dem SARS-Coronavirus und der humanene Wirtszelle. Zweites BMBF Statusseminar („SARS: Ökologie und Pathogenese einer archetypischen Zoonose“), 11.04.2008, Bonn.

von Brunn, A, Ester, C, Schöpf, J, Uetz, P and Haas, J. Analysis of Intraviral Protein-Protein Interactions of the SARS Coronavirus ORFeome by peptide scanning. Jahrestagung der Gesellschaft für Virologie (GfV) in Heidelberg, 5.-7.-3.-2008

von Brunn A, Teepe C, Simpson JC, Pepperkok R, Friedel CC, Zimmer R, Roberts R, Baric R, Haas J. Analysis of Intraviral Protein-Protein Interactions of the SARS Coronavirus ORFeome. Third European Congress of Virology in Nürnberg, 1.-5.-9.2007